Fierer Lab

Exploring the structure and function of microbial communities

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Insights, rants, shameless self promotion, etc. from the Fierer lab and its affiliates.

The ‘hidden’ costs of microbial community analyses

February 13th, 2019 By: Noah Fierer DNA sequencing is clearly a powerful tool for analyzing microbial communities. It is now somewhat routine to take a sample of feces, tap water, or bellybutton lint and use DNA sequencing-based approaches to analyze the microbes living therein. We also know that the cost of generating DNA sequence data

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Garbage in, garbage out: Wrestling with contamination in microbial sequencing projects

August 15th, 2018 By: Noah Fierer, Jessica Henley, and Matt Gebert   They are insidious. They are difficult to eliminate. They strike fear in the hearts of microbiologists worldwide.  Hard drive failures? Third reviewers? Bedbugs lurking in conference hotels? Nope. Contaminants in your high-throughput sequence data. High-throughput sequencing approaches are now routinely used to characterize

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Do all animals need microbes?

By Tobin Hammer, Jon Sanders, & Noah Fierer May 18th, 2018   Have you—like us—ever written a paper or grant proposal with a statement along the lines of “All animals host microbial symbionts that play critical roles in many aspects of host ecology, behavior, and development”? If so, this blog post is for you. We

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Is RNA a useful measure of microbial activity?

December 20, 2017 By Noah Fierer Let’s say a microbial ecologist wants to identify which bacteria are active in a given environmental sample at a given point in time. For example, you may want to determine which bacteria are active in a desert soil after a large rainfall event. This is often done by comparing

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